Propionate is an important platform chemical that is available through petrochemical synthesis.Bacterial propionate formation is considered an alternative, as bacteria can convert waste substrates into valuable products.In this regard, research primarily focused on propionibacteria due to high propionate titers achieved from different substrates.Wh
An Evaluation of Local Pharmaceutical Manufacturing in Zimbabwe: How Prepared is Zimbabwe to Produce COVID-19 Vaccines?
Globally, the COVID-19 pandemic has had a significant impact, given the rise in the demand for novel therapeutics such as vaccines that can be used in the treatment of COVID-19 patients.Compared to other regions of the world, gross vaccine Vegetable garden inequity exists in Africa due to several factors tied to the acute lack of vaccines in the re
Genetically engineered probiotics as catalytic glucose depriver for tumor starvation therapy
Cancer cells predominantly adapt the frequent but less efficient glycolytic process to produce ATPs rather Stock Pads than the highly efficient oxidative phosphorylation pathway.Such a regulated metabolic pattern in cancer cells offers promising therapeutic opportunities to kill tumors by glucose depletion or glycolysis blockade.In addition, to gua
Use of WHO clinical stage for assessing patient eligibility to antiretroviral therapy in a routine health service setting in Jinja, Uganda
Abstract In a routine service delivery setting in Uganda, we assessed the ability of the WHO clinical stage to accurately identify HIV-infected patients in whom antiretroviral therapy should be started.Among 4302 subjects screened for ART, the sensitivity and specificity (95% CI) of WHO stage III, IV against a CD4 count 6/l were 52% (50, 54%) and 6
Adaptation in the auditory system: an overview
The early stages of the auditory system need to preserve the timing information of sounds in order to extract the basic features of acoustic stimuli.At the same time, different processes of neuronal adaptation occur at several levels to further process the auditory information.For instance, auditory nerve fiber responses already experience adaptati